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Emerging insights into the complex genetics and pathophysiology of amyotrophic lateral sclerosis

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It has been shown that several vitiligo-related autoantigens are present in the serum or skin lesions of vitiligo patients, including tyrosinase hydroxylase, tyrosinase antigen, tyrosine-related proteins (TRP1 and TRP2), melanocortin 1 receptor (MC1R), melanoma-associated antigen 1, pre-melanosomal protein 17, and melanocyte transcription factor SOX10 (Xie et al., 2016)